Metoprolol succinate is a drug used to treat high blood pressure and angina. This form of the drug is an extended-release version that allows a steady release of medication into the bloodstream. Because this drug might cause undesirable side effects and because it is in short supply in some areas, an alternative to metoprolol succinate might be necessary for some patients.
Metoprolol Tartrate
One alternative to metoprolol succinate is metoprolol tartrate, which is the version of the drug that immediately releases medication into the bloodstream. According to information contained in the Pharmacist's Letter/Prescriber's Letter, metoprolol tartrate is also used to treat hypertension and angina. It is also approved as a drug to be given after heart attacks to reduce the workload on the heart. Because the drug is immediately released, only one dose of metoprolol tartrate might not be enough to control high blood pressure. In cases where a patient might have difficulty remembering to take a second dose of medication, another alternative to metoprolol succinate might be necessary.
Beta Blockers
According to the Mayo Clinic, beta blockers work to reduce blood pressure. While metoprolol is a beta blocker, other drugs in this class also can lower blood pressure without the effects of metoprolol succinate. These drugs include atenolol, nadolol and bisoprolol. Beta blockers block the effects of adrenaline and slow the heart, which reduces the blood pressure. These drugs also improve blood flow by opening up the blood vessels.
Diuretics
Diuretics might be used alone or in combination with other drugs to reduce . According to Dr. Richard E. Klabunde of Cardiovascular Pharmacology Concepts, diuretics can be used to treat hypertension because they reduce blood volume, resistance of the blood vessels and cardiac output. This reduces the workload on the heart and leads to lower blood pressure. The three types of diuretics that can be used to treat high blood pressure include thiazide diuretics, loop diuretics, and potassium-sparing diuretics.
ACE Inhibitors
According to the Mayo Clinic, angiotensin-converting enzyme (ACE) inhibitors can be used to treat high blood pressure and may be a suitable alternative to metoprolol succinate. ACE inhibitors relax the blood vessels by preventing the production if angiotensin II, which narrows the blood vessels and can increase blood pressure. Some of the ACE inhibitors available include enalapril, quinapril, captopril and lisinopril.
Calcium Channel Blockers
According to the American Heart Association, calcium channel blockers can relax blood vessels and reduce how hard the heart has to pump, which makes them a good choice for the treatment of high blood pressure. Calcium channel blockers slow the rate of calcium passing into the heart muscle and into the walls of the blood vessels. Examples of calcium channel blockers include verapamil, isradipine, and amlodipine.
Tags: blood pressure, blood vessels, high blood, high blood pressure,